Search on: S-PHASE KINASE-ASSOCIATED PROTEINS 
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Descriptor English:   S-Phase Kinase-Associated Proteins 
Descriptor Spanish:   Proteínas Quinasas Asociadas a Fase-S 
Descriptor Portuguese:   Proteínas Quinases Associadas a Fase S 
Tree Number:   D12.776.157.743
Definition English:   A family of structurally-related proteins that were originally identified by their ability to complex with cyclin proteins (CYCLINS). They share a common domain that binds specifically to F-BOX MOTIFS. They take part in SKP CULLIN F-BOX PROTEIN LIGASES, where they can bind to a variety of F-BOX PROTEINS. 
History Note English:   2004; use S-PHASE KINASE ASSOCIATED PROTEINS (NM) 1983-2003; for P19(SKP1)PROTEIN and P45(SKP) PROTEIN use S-PHASE KINASE ASSOCIATED PROTEINS (NM) 1995-2003; for P45(SKP) use UBIQUITIN-PROTEIN LIGASES (NM) 1999-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38256 
Unique Identifier:   D044786 

Occurrence in VHL:
 

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